People with disabilities who have problems accessing the FOLLOWING PDF files can contact the assistance at (301) 796-3634. You`ll find information about historical and shared rems in the download: Data Files. Many products in these REMS programs have medication guides that are not part of the REMS program. Here is a complete list of medication guides. The following table contains links to the individual and shared system REMS currently allowed. The Food and Drug Administration Amendments Act of 2007 gave the FDA the authority to require a risk assessment and mitigation (REMS) strategy from manufacturers to ensure that the benefits of a drug or organic product outweigh its risks.